Archives Ouvertes HAL

Toutes les publications de l'ENAC en direct.
All ENAC publications.

[hal-01643260] The Dispersion of Superposition Coding for Gaussian Broadcast Channels

Publications ENAC - Tuesday, 21 November 2017 - 14:03:42
In this paper, we analyze the performance of superposition coding for Gaussian broadcast channels with finite blocklength. To this end, we adapt two different achievability bounds, the dependence testing and the κβ bounds introduced by Polyanskiy et al. in 2010 to the broadcast setting. The distinction between these bounds lies in fixing either the input or the output distributions of the channel. For the first case of the dependence testing bound, an upper bound on the average error probability of the system is derived whereas for the latter, lower bounds on the maximal code sizes of each user are presented.

[hal-01643256] $κβ$ Bounds for Gaussian Broadcast Channels with Finite Blocklength

Publications ENAC - Tuesday, 21 November 2017 - 14:02:34
We analyze the achievable performance of superposition coding in a two–receiver Gaussian broadcast channel (BC) with finite blocklength. To this end, we adapt the achievability bound on maximal code size of a point-to-point (P2P) channel introduced by Polyanskiy et al. in 2010 to the broadcast setting. Additionally, a new converse bound on maximal code sizes of each user in a two-user Gaussian BC is introduced for a given probability of error.

[hal-01643287] Combining two-dimensional gel electrophoresis and metabolomic data in support of dry-season survival in the two main species of the malarial mosquito Anopheles gambiae $

Publications ENAC - Tuesday, 21 November 2017 - 13:48:58
In dry savannahs of West-Africa, the malarial mosquitoes of the Anopheles gambiae sensu stricto complex annually survive the harsh desiccating conditions of the dry season. However, the physiological and biochemical mechanisms underlying how these mosquitoes survive such desiccating conditions are still undefined, and controversial. In this context, we provide the first work examining both proteomic and metabolomic changes in the two molecular forms of A. gambiae s.s (M and S forms) experimentally exposed to the rainy and dry season conditions as they experience in the field. Protein abundances of the mosquitoes were measured using a two-dimensional fluorescence...

[hal-01637213] Supramolecular catalysis. Part 2: artificial enzyme mimics

Publications ENAC - Tuesday, 21 November 2017 - 13:25:41
The design of artificial catalysts able to compete with the catalytic proficiency of enzymes is an intense subject of research. Non-covalent interactions are thought to be involved in several properties of enzymatic catalysis, notably (i) the confinement of the substrates and the active site within a catalytic pocket, (ii) the creation of a hydrophobic pocket in water, (iii) self-replication properties and (iv) allosteric properties. The origins of the enhanced rates and high catalytic selectivities associated with these properties are still a matter of debate. Stabilisation of the transition state and favourable conformations of the active site and the product(s) are...

[hal-01643281] Éthique de la recherche en apprentissage machine

Publications ENAC - Tuesday, 21 November 2017 - 13:13:43
Dans le numérique, le foisonnement et la rapidité de déploiement des usages issus de l’innovation contribuent à la complexité de l’interaction entre l’offre technologique et l’appropriation par la société, et réduit de ce fait la portée des prévisions scientifiques sur les conséquences de la recherche. Cette relative imprévisibilité des usages ne doit pas dédouaner les scientifiques, mais doit au contraire motiver la réflexion éthique et la recherche d’attitudes et de méthodes adaptées. En effet les chercheurs doivent avoir à l’esprit que leurs travaux contribuent de facto à transformer la société et peut-être l’Homme, comme l’ont fait beaucoup d’outils et de techniques...

[hal-01637955] Optimal location of temporary military zones within civil aviation traffic

Publications ENAC - Tuesday, 21 November 2017 - 12:19:25
In this study, we focus on the problem of locating optimally temporary military zones with the aim of minimizing the number of civil flight trajectories impacted by the military activity, and the distance between the military zone and the military base. We model the military zones by 2D geometry shapes with a vertical extension associated to given flight levels during the temporary zone-activation time window. We propose a mathematical formulation of this problem as a constrained-optimization problem. We then introduce a global optimization methodology based on a simulated annealing algorithm featuring tailored neighborhood-search strategies. This is applied to one day...

[hal-01643040] Predictive biomarkers of resistance to hypofractionated radiotherapy in high grade glioma

Publications ENAC - Tuesday, 21 November 2017 - 10:36:23
Background: Radiotherapy plays a major role in the management of high grade glioma. However, the radioresistance of glioma cells limits its efficiency and drives recurrence inside the irradiated tumor volume leading to poor outcome for patients. Stereotactic hypofractionated radiotherapy is one option for recurrent high grade gliomas. Optimization of hypofractionated radiotherapy with new radiosensitizing agents requires the identification of robust druggable targets involved in radioresistance. Methods: We generated 11 xenografted glioma models: 6 were derived from cell lines (1 WHO grade III and 5 grade IV) and 5 were patient derived xenografts (2 WHO grade III and 3...

[hal-01643043] Global Conservation of Protein Status between Cell Lines and Xenografts

Publications ENAC - Tuesday, 21 November 2017 - 10:17:49
Common preclinical models for testing anticancer treatment include cultured human tumor cell lines in monolayer, and xenografts derived from these cell lines in immunodeficient mice. Our goal was to determine how similar the xenografts are compared with their original cell line and to determine whether it is possible to predict the stability of a xenograft model beforehand. We studied a selection of 89 protein markers of interest in 14 human cell cultures and respective subcutaneous xenografts using the reverse-phase protein array technology. We specifically focused on proteins and posttranslational modifications involved in DNA repair, PI3K pathway, apoptosis, tyrosine...

[hal-01643049] Fractionated stereotactic radiotherapy of benign skull-base tumors: a dosimetric comparison of volumetric modulated arc therapy with Rapidarc® versus non-coplanar dynamic arcs

Publications ENAC - Tuesday, 21 November 2017 - 10:06:47
Background: Benign tumors of the skull base are a challenge when delivering radiotherapy. An appropriate choice of radiation technique may significantly improve the patient’s outcomes. Our study aimed to compare the dosimetric results of fractionated stereotactic radiotherapy between non-coplanar dynamic arcs and coplanar volumetric modulated arctherapy (Rapidarc®). Methods: Thirteen patients treated with Novalis TX® were analysed: six vestibular schwannomas, four pituitary adenomas and three meningioma. Two treatment plans were created for each case: dynamic arcs (4–5 non coplanar arcs) and Rapidarc® (2 coplanar arcs). All tumors were >3 cm and accessible to both...
Back to top